What disadvantage do these enzymes have over crispr-cas9

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Assignment:

QUESTION 1: Can you please give an elaborate answer to the following questions?

a) What endonucleases are capable of binding long non-asymmetric DNA sequences and causing a Double Strand Break?

b) Which endonuclease has been utilised successfully in yeast to repair double-strand breaks via HDR?

c) In the context of precision genome editing, what disadvantage do these enzymes have over CRISPR/Cas9?

Reference no: EM133312203

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