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What change might be made in drug administration

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A patient is 29 weeks pregnant with her first child. She was recently hospitalized for a severe manic episode during which she put her and baby's life in danger. After careful consideration with many health care professionals, she has made the decision to restart lithium, a drug that is excreted almost exclusively by the kidney. Prior to pregnancy, this patient had been successfully maintained on a lithium dose of 300 mg, PO, three times daily. Given the pharmacokinetic changes that occur as pregnancy progresses, what change might be made in drug administration?

Reference no: EM133565990

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