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Chronic inflammation is responsible for auto-immune, and other, diseases. In pathogenic inflammatory diseases, high levels of immune cells (macrophages, neutrophils, and TH1 cells) migrate from the blood to the tissue over a prolonged period of time. Most articles recently published on this subject focus on inhibiting TH1 migration. Yet, TH1 cells do not directly cause tissue damage. What cells are activated by TH1 cytokines, and what do these cells do to cause damage?
Explain two reasons why kidney failure can affect calcium homeostasis. List 2 things that can help to increase bone formation in the elderly.
Explain pulse pressure in terms of changes in systolic and diastolic pressures and why pulse pressure increases during exercise?
Briefly explain bacterial disease, viral disease, fungal disease and parasitic disease, and give an example of each.
Analysis of preserved leaves shows that the density of stomata per unit area has decreased over the past 200 years. Suggest (and support) a hypothesis that explains this phenomenon.
Some enzymes like papain have a very flat pH profile i.e. they have nearly the same activity over a very broad pH range. what might this flat pH profile suggest about the amino acids active site of the enzyme papain?
Fully explain why the excessive use of antibiotics may lead to nutritional disorders in humans.
Tay Sachs, an autosomal recessive genetic disease in humans has a frequency (q2, assuming random mating) of about 2x10-6; assuming random mating, therefore, the frequency of the Tay-Sachs allele, q is about 1.4x10-3 . Tay-Sachs sufferers usually d..
A second-order reaction of the type A+2B -> P was caried out in a solution that was initally 0.075mol L^-1 in A and 0.030 mol L^-1 in B. Afer 1.0 h the concentration of A had fallen to 0.045 mol L^-1.
Blood flow (liters per min.) through the pulmonary circuit equals blood flow through the systemic circuit, but pulmonary resistance to flow is 5 times less than the systemic resistance to flow so by using the mean arterial pressure equation, show ..
Which wavelengths of visible light carry the most energy? How does this relate to strategies for plant photosynthesis? Why was it important to mark the TLC plate with pencil?
if dividing cell is labelled with 32P, in which DNA molecules will the radioactivity be incorporated during metaphase? After replication, in which DNA molecules will the radioactivity be present?
The D. melanogaster genome consists of approximately 1.7 x 108 base pairs. If DNA synthesis occurs at a rate of forty base pairs per second, and the entire genome is replicated in ten minutes,
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