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a) What are the major proofreading steps during the process of translation? (hint: we talked about two different steps in which proofreading is involved) What might happen if one or the other are not functioning correctly?
b)What are the wobble rules? If given a codon or anticodon, could you provide the appropriate anticodon or codon respectively?
c)Overall how does translation compare in bacteria and eukaryotes? Are there steps that are similar? Different? Explain.
How do 2 tryptophans interact with each other? What other amino acids exhibit similar behavior?
Consider brown eyes dominant to blue. A blue-eyed man both of whose parents were brown-eyed marries a brown-eyed woman. They have one child who is blue-eyed. What are the genotypes of all the individuals mentioned?
Describe the three main cellular components of the blood and explain what might cause abnormal numbers of each of these components.
What mutations in the amino acid sequence would probably have the least detrimental effect on the functionality of the protein?
Suppose that a mutation occurred in the SRY gene on the human Y chromosome, knocking out its ability to produce the testis-determining factor. Predict the phenotype of an individual who carried this mutation and a normal X chromosome.
Why are echinoderms classified as animals? Please don't give half answers or meaningless answers.
If, in addition to the N-terminal fragment of Groovy, a cell also makes an equal amount of the full-length protein, what is likely to happen to transcription of the Zippy gene (increase, decrease or stay the same)?
Suppose that you are working with Drosophila and are studying genes, a, b, c, d, e, and f that are all linked in a region on a chromosome, but their order is unknown.
Which strand of DNA is transcribed and in which direction? Show your reasoning.
What kind of error in Meiosis could lead to two copies of a single chromosome in a sperm or egg rather than the expected one?
What is the probability that, in an organism with a haploid number of 15, a sperm will be formed that contains all 15 chromosomes whose centromeres were derived from maternal homologs?
At a talk by a visiting scientist, you learn about a strain of bakers' yeast that contains a mutation called gal1- in its galactokinase gene. Because this gene is needed to metabolize galactose, the mutant strain cannot grow in galactose medium.
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