What are the stated confidence intervals or p values

Reference no: EM133619726

Problem

Reference : Papi, A., Ison, M. G., Langley, J. M., Lee, D. G., Leroux-Roels, I., Martinon-Torres, F., Schwarz, T. F., van Zyl-Smit, R. N., Campora, L., Dezutter, N., de Schrevel, N., Fissette, L., David, M. P., Van der Wielen, M., Kostanyan, L., & Hulstrøm, V. (2023, February 16). Respiratory Syncytial Virus Prefusion F Protein Vaccine in Older Adults. New England Journal of Medicine, 388(7), 595-608.

Are the findings believable?
What are the important findings?
Will the study help my patients?

A. Title Analysis and Study Type: Dose the article reflect the purpose of the study including the implications for patient management in the clinical setting? Are there multiple researchers and is this study peer reviewed? Identify evidence of peer review within the publication. Is this a single site or multi-center study?

B. State the research (HA) and null (Ho) hypotheses for this study.

C. Describe the Researchers: Are the researchers' clinicians? Do they appear to have expertise for this patient population and the specialized instrumentation used for data collection?

D. Describe Research Design: Does this study reflect "true" human subject research or is this study an analysis of previously collected data? Comment on the methods used to assign the subjects to the study groups. Was there a Control and Experimental group(s). Are the "n's" for groups comparable? Is this an example of dichotomous research?

E. Summarize the Statistical Methods: What are the stated confidence intervals (CI) or p values. What Statistical tool(s) was/were used to compare or summarize the results. Are the limitations appropriate for this study, in your own opinion?

F. Critique of Conclusions: Finally, after review do you support the authors' stated Conclusions? State your support or reservations regarding their Conclusions. Could this study be generalized to guide your Practice?

Reference no: EM133619726

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