Reference no: EM133148061

Question 1) Provide an experimental description of what you did. (As you would find in the supporting information of a journal article). This should include NMR data and a yield.

Question 2) Draw a curly arrow mechanism for this reaction (shows how both regioisomers are derived, if appropriate).

Question 3) Copy your TLC here with labels: include the description of each spot, the solvent system and the Rf value for each spot, mark on where the solvent front is. You could attach a photo instead if you prefer but still annotate.

Question 4) What were the key input choices for setting up the microwave reactor and what do they mean? Your answer should give a title of the parameter and then 1 or 2 sentences about what that parameter is, repeat for all parameters observed on the MW reactor interface.

Question 5) What are the benefits of using a microwave reactor compared to standard thermal synthesis?

Question 6) Affix your ANNOTATED 1H NMR spectrum to this page. Annotation includes a drawing of the expected compound and assignment of the peaks. What is the observed regioselectivity (if applicable).

Question 7) Affix your ANNOTATED 13C NMR spectrum to this page. Annotation includes a drawing of the expected compound and assignment of the peaks, full assignment may be difficult with a mixture.

Question 8) What were the key input choices for setting up the Automated purification equipment? and what do they mean? Your answer should give a title of the parameter and then 1 or 2 sentences about what that parameter is, repeat for all parameters observed on the auto-purification interface

Question 9) What are the main advantages of using an automated column over traditional flash column chromatography?

Question 10) List all the compounds that your group made, and comment on different rf, yield among the different products. (access all this information in the discussion board in LC)

Question 11) Briefly describe how the compound series covers the potential to explores SAR