What are important characteristics of the disease

Assignment Help Other Subject

Reference no: EM131443775

You are a researcher at Advanced Bio Delivery Systems (ABDS), a company that supplies vectors for use in gene therapy. The marketing department has come to you for assistance. They would like to sell the vectors made by ABDS to biotech companies pursuing specific gene therapies. It is your job to research the disorders these biotech companies are targeting and decide on a vector that has potential to work. You will be presenting your findings to the marketing department for approval. There may be more than one vector possibility, so your job is to choose what you feel is the best one and defend your position. Your company stands to make a considerable profit if you are able to "sell" their vector for use in research.

Activity Details

Acting as employees of a vector supply company, research a disease that is a candidate for gene therapy and determine the best vector to use. You must then present your choice in a brochure and the reasoning behind it in order to help "sell" the vector to a biotech company developing a therapy for this disease.

Here are some choices for diseases and genes to research but feel free to select your own:

neurofibromatosis type 1 and the NF1 gene
hemophilia and blood clotting factors
non-small cell lung cancer and p53, a tumor suppressor gene
SCID and ADA gene

Some things to consider for your brochure:

What are important characteristics of the disease being investigated (genetic defect, body system affected...)?

Will the gene fit into the vector?

What types of cells would the therapy need to target (dividing/non-dividing)?

What will happen to the genetic material once it is inserted into the cells?

Does gene expression need to last a long time?

What kinds of safety issues need to be considered before recommending a vector type?

A tool to create your 3-Panel brochure is is linked: Brothers Creative Center. You can also use the brochure template on any word processing program--Word or Google docs. Just make sure that the file is in a readable format for everyone before you submit it.

Post your completed brochure by the end of Week 9.

Review the brochures posted by your peers. Share thoughts on the brochures. Leave comments to at least two brochures. You can use the following questions to direct your comments:

Were important characteristics of the disease addressed and described in detail?

Were important characteristics of the vector addressed and described in detail?

Will the vector chosen bind to the target cells? Was the description of targeting strategy detailed?

Did the brochure include a detailed description of what will happen to the DNA as it is integrated into the cell?

Reference no: EM131443775

Questions Cloud

Define the identified critical step of research in your word : Bullying is a difficult concept to understand and reconcile the consequences. This assignment focuses on the critical thinking skills that are needed to analyze an emotionally charged topic.Watch the video titled, "From school yard bullying to gen..

Discuss papa john from a strategic perspective : In a narrative format, discuss Papa John's from a strategic perspective. Information concerning recent changes in the firms is readily available online and should be accessed. Strategic issues should be discussed in "real time."

Is the combination of beer and beef possible : Given the information above, what is the opportunity cost of the 55th keg of beer in Alberta? Of the 6th side of beef? Of the 9th side of beef?

Components of a single-business company strategy : In evaluating how well a company's present strategy is working, a manager has to start with the strategy. Figure 4.1, Identifying the Components of a Single-Business Company's Strategy, in your textbook, shows the key components of a single-busine..

What are important characteristics of the disease : Some things to consider for your brochure: What are important characteristics of the disease being investigated (genetic defect, body system affected...)? Will the gene fit into the vector? What types of cells would the therapy need to target (dividi..

Determining the verbal or nonverbal feedback : Indicate at what point you would have given her verbal or nonverbal feedback, and what form it would take. Then, paraphrase her response, looking for the essence of the complaint. Imagine that you are talking directly to the customer as you type y..

Discuss about the important doctrines in buddhism : Two of the most important doctrines in Buddhism, which are at the root of most Buddhist teachings, are those of anatta, or no self, and dependent origination or pañicca-samuppàda. Because most of us are coming to these doctrines from a Western poi..

Marketing officer for a large international organization : You are the chief marketing officer for a large international organization that provides service to over 25,000 retail outlets. Management wants to improve sales by increasing business with existing customers and getting new customers as well. You..

Tradeaccording to comparative advantageis : Do you agree or disagree with the following statement, and why? "Tradeaccording to comparative advantageis fine if you are a productivity leader, but if not, then it will destroy your industries and create only losses".

User Account

All Pages