What are immune receptors to depend on co-receptors

Reference no: EM133290645

Assignment:

Please answer the questions below. Please type out the full answer and explanation.

Question

A. What are the reasons for immune receptors to depend on co-receptors and even work with different co-receptors?

B. IL-4R is an IL-4 receptor. When expressed in resting macrophages, it binds to IL-4 with low affinity, but when expressed in macrophages exposed to LPS, it binds to the same cytokine with high affinity. How might this be possible?

Reference no: EM133290645

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