What additional change to primary protein structure

Assignment Help Biology
Reference no: EM133261593

In humans, PFKR is a protein that is secreted from cells. A team of scientists decide to redirect PFKR to the inside of the nucleus instead of having it secreted. The scientists change the primary protein sequence so that it is no longer secreted from the cell (it remains in the cytosol), but unfortunately, the modified protein does not enter the nucleus.

1. Describe what additional change(s) to the primary protein structure you would suggest to ensure that PFKR reaches the inside of the nucleus.

2. Describe the path PFKR, outlined in (A) above, would take to reach the inside of the nucleus. Start your description from the place in the cell where protein synthesis begins. Include all relevant cell regions and/or structures in your description.

Reference no: EM133261593

Questions Cloud

Discuss pharmacological versus non-pharmacological nursing : Discuss pharmacological versus non-pharmacological nursing interventions used for pain management during labor and birth. List two different classifications of
What bifurcations are visualized : 1. What arteries are visualized and which section of that artery is best visualized (prox, mid, distal)
Discuss importance of international perspectives in research : Educators need to support students' growth in international and global perspectives. Discuss importance of international perspectives in research
Represents the time needed for sinus node stimulation : This is from clinical manifestations and dr studies section for med surge nursing . Please be sure to be as detailed as possible in your explanation.
What additional change to primary protein structure : Describe what additional change(s) to the primary protein structure you would suggest to ensure that PFKR reaches the inside of the nucleus.
Discuss the principles of access and equity : Discuss the principles of access and equity. Why are they important in mental health work?
What is the role of the gallbladder : A 32-year-old-female who recently delivered twins presents with colicky type pain, URQ pain radiating to the shoulder. After workup, she is diagnosed with chole
Compare the united states healthcare system : Compare the United States healthcare system with those of other nations and describe similarities and differences. Please provide reference not more than 5years
Chocolate happiness undergoing more pleasantness : Read the CHUMP (Chocolate Happiness Undergoing More Pleasantness) article before responding.

Reviews

Write a Review

Biology Questions & Answers

  Immune response to infectious disease

It is a very curcial concept to understand how the immune response is mounted against viruses, bacteria, protozoans and helminthes. For an effective immune response, both innate and adaptive immunity should work together.

  A review on advanced glycated end products (ages)

This Project report elaborates a critical review of important elements attached to Advanced Glycated End Products (AGEs). It is very crucial to understand the process called Millard reaction.

  Plastic as a soil stabilizer

Soil stabilization is the permanent physical and chemical alteration of soils to enhance their physical properties. Stabilization can increase the shear strength of a soil and control the shrink-swell properties.

  Principles of microbiology

This assignment has three parts which contains questions related to Microbiology. It contains basic principles of microscopy, staining techniques in microbiology and microbial growth in the food industry.

  List the biologic functions

Lipid metabolites are often seen as key elements in cellular signaling. Is this unique? Please provide several examples of the function of lipids as key elements in signal arrays and list the biologic functions these signals affect?

  Biologic function relationships

Please describe how one might search for chemical structure, biologic function relationships, involving small molecular weight lipophylic compounds. Provide one example.

  Case study on patient in the haematology laboratory

Write a case study which detailing a scenario of a patient being investigated in the Haematology laboratory.

  Use of pcr and genetic approaches in biotechnology

The use of PCR and genetic approaches in biotechnology

  Describe the role of this enzyme in honey

Glucose oxidase is an enzyme that can be used for measurements of glucose levels by combining this reaction with an oxygen probe.

  Genetic problems

What phenotypic ratio would you get if you crossed a white mouse and a heterozygous brown mouse?

  Prepare an essay on nosocomial infection

Prepare an essay on nosocomial infection.

  Monitoring and recording the blood pressure

To increase the awareness of monitoring and recording the blood pressure of patients and practice measuring blood pressure in a safe environment.

Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd