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1) Horace Jones had a colonoscopy shortly after his 50th birthday, and the gastroenterologist noticed an unusual mass of tissue in the region of the sigmoid colon. Subsequent tests and surgery revealed that the mass was malignant, having invaded the submucosal and muscularis layers of the colon. Biopsy of regional lymph nodes was positive, with 2 nodes showing tumor cells.a. What kind of cancer does Mr. Jones have, and what Stage is his cancer?b. If you looked at a tissue slide, what are the likely differences in appearance between tumor cells from his cancer and normal cells from other parts of the colon?2) In general, a change in a single allele of an oncogene can result in tumor growth or cancer, while it takes two changes in both alleles of tumor suppressor genes.a. How do you explain this difference?b.What do these genes code for normally? That is, in a healthy person, what role are the oncogenes and tumor suppressor genes playing, and how do they do it? 3) Hepatitis B, Human Papilloma Virus, Epstein-Barr Virus, and Kaposi sarcoma-associated herpesvirus are all associated with cancer, and are all DNA viruses.a. Are these two facts incidental, or does one help explain the other?b. Another virus associated with cancer is HTLV (Human T cell leukemia-lymphoma virus), which is a retrovirus. How does this relate to the DNA viruses in the list?c.Why do only a small fraction of those infected with one of these viruses develop cancer?
Suppose that the lengths of the double-helical regions and the lengths of the single-stranded regions in them vary within relatively tight limits.
The allele l in Drosophila is recessive, sex-linked, and lethal when homozygous or hemizygous (the condition in males). If a female of genotype L/l is crossed with a normal male, what is the probability that the first two surviving progeny will be..
Assume you treated butter with a fatty acid desaturase, an enzyme that removes hydrogen from fatty acids and creates double bonds.
If you wanted 10mL of a 1mM nitrophenol solution and you have on hand a 50mM nitrophenol solution, how would you make it. If you wanted 100mL of a 0.1M acetic acid solution, how much 17.4M acetic acid and how much water do you need to add to make t..
When true breeding pea plants with yellow seeds are crossed to plants that have green seed, all the offspring produce yellow seed.
Robert, a smoker, is 52 years old. He has elevated blood pressure, in part, due to an elevated erythrocyte count. Knowing that smokers often have reduced plasma O2 levels, explain in detail (in a paragraph) why his erythrocyte count is elevated.
Two consecutive crosses, with the first between pure-breeding parents that differ in two phenotypes to create an F1 generation, and the second in two F1 progeny to create an F2 generation.
Write the sequence of the peptide fragments that would beformed if β-endorphin was treated with pepsin?
Explain 4 mechanisms by which the integument helps to prevent infection. In other words, explain either specific actions the integument performs or characteristics of its structure.
What is wetland mitigation? How is it different from wetland restoration and what is the main mitigation goal of the usfws for this project? Is this goal a direct response to the pollutant release at the re? nery
A patient lost a lot of blood during surgery and his blood pressure dropped from 120/80 to 90/50. Describe how the kidneys respond to this change in blood pressure.
A population of cats can be either black or white; the black allele has complete dominance over the white allele. Given a population of 1,000 cats.
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