Understanding enzyme function

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  1. You believe a substrate fits into a cleft like a key into a lock, but your roommate does not. Who is right?
  2. If Keq = 1, what is the ?Go´? 
  3. If Keq > 1, what is the ?Go´? 
  4. If Keq < 1, what is the ?Go´?
  5. How is the overall free energy of a reaction useful for understanding enzyme function?
  6. What are transition-state analogs?
  7. How does binding of substrate molecules to the active site in enzymes facilitate the formation of the transition state?
  8. Describe the difference between the concerted and the sequential model of allosteric regulation.
  9. What is the Michaelis-Menten equation? Define all parameters.
  10. Compare the difference between the reversible inhibitors competitive, noncompetitive or mixed, and uncompetitive inhibitors

Reference no: EM132439808

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