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Assignment:
A 52-year-old man with a past medical history of pre-diabetes, schizophrenia, and hypertension was enrolled in a research study at 32 years of age. He was subjected to a series of brain CT and MRI scans. These scans mapped out specific neural connections and the strengths of those signals at baseline. Today the patient has alcohol use disorder and substance use disorder. He drinks 2 bottles of wine a day and occasionally smokes marijuana. While entering rehab, he is subjected to the same mapping scans from 20 - years earlier to evaluate for changes in those specific neural connections. Of the types of changes possible in the plasticity of neural connections, which would propagate the patient's addiction, and can it be reversed?
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