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Thermus aquaticus is a thermophilic bacterium that grows between the temperatures of 50 and 80°C. Although the signal peptide binding groove of its Ffh M domain is lined with hydrophobic groups, only three of them are Met side chains. In contrast, the binding grooves of mesophilic organisms (those that live at normal temperatures) are lined with numerous Met side chains (11 in E. coli). In addition, the finger loop forming one wall of the binding groove is disordered in the X-ray structure of the E. coli M domain but ordered in that of T. aquaticus (Figure 12-48 in Voet; both proteins were crystallized at room temperature). Suggest a reason for these evolutionary adaptations in T. aquaticus
Osmometer cells in the brain sense an increase in concentration of the blood plasma. They then notify the posterior pituitary gland to release the hormone, ADH. This hormone causes the kidney to save water that lowers the concentration of the plasma.
Discuss how do use the factor-label method to calculate the number of grams of KMnO4 that you would need to make 100 ml of a 0.0045 M potassium permanganate solution?
If a double heterozygous plant were crossed with a plant that has green stems and red fruit, what offspring phenotypes would be expected and in what proportions.
In Drosophila a cross was made between a yellow-bodied male with vestigial (not fully developed) wings and a wild-type female (brown body). The F1 generation consisted of wild-type males and wild-type females.
What are the two exceptions to the general rule that all cells in the human body contain a complete, identical copy, of a person's DNA?
What results of the Cassini radar mapping of Titan have provided the strongest evidence so far for liquid bodies on its surface.
Name the bones of pectoral girdle and the bones of the pelvic girdle. Evaluate the pectoral and pelvic girdles with regard to strength, versatility, and function.
Determine the pathophysiology for intrinsic vs extrinsic asthma? Are they both IgE mediated and Write out the overall chemical reaction of cellular respiration.
determine the genotypes of the two parents: A) a walnut crossed with a single produces offspring that are ¼ walnut, ¼ rose, ¼ pea, and ¼ single.
I in brief describe how a mutation might alter gene function (at the molecular level) if it fell into the following categories. As an example, a neomorphic mutation could result from expressing a gene in a novel location.
Ion concentrations have a impact on whether there is dissolution of minerals. Microorganisms can alter the charges on their cell surfaces to enhance these processes.
Assume you are studying genes and DNAsequences involved in the regulation of the grandoperon. When your lab's strain of e. coli are in the presence of the sugar "grandiose," transcription of 2-enzymes grandAand grandB increases.
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