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The receptor sites for opioids consist of three receptors

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The receptor sites for opioids consist of three receptors: mu, kappa, and delta which are located on nerve cells. Opioids can act at these receptors as agonists, antagonists or partial agonists.

Morphine has the greatest affinity for mu receptors.

Narcan is the most commonly used opioid antagonist and acts on all three receptor sites. Narcan attaches to opioid receptors and prevents activation of them, thereby reversing and blocking the effects of other opioids.

How does Narcan work on the receptor site, as an agonist, antagonist or partial agonist?

Reference no: EM133280388

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