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The gene that encodes the enzyme called tyrosine hydroxylase is known to be up regulated by the CREB protein. Tyrosine hydroxylase is expressed in nerve cells and is involved in the synthesis of catecholamine, a neurotransmitter. The expose of cells to adrenaline normally up regulates the transcription of the tyrosine hydroxylase gene. A mutant cell line was identified in which the tyrosine hydroxylase gene was NOT up regulated when exposed to adrenaline. List all the possible mutations that could explain this defect. How would you explain the defect if only the tyrosine hydroxylase gene was not up regulated by the CREB protein, whereas other genes having CREs were properly up regulated in response to adrenaline in this cell line?
Describe why it may be too simplistic to label disease-causing alleles as "bad" and corresponding "normally" functioning alleles as "good."
A porcupine eats 3,000 J of plant material. 1,600 J is indigestible and is eliminated as feces. 1,300 J are used in cellular respiration. What is the estimated production efficiency of this animal.
Which of the following could theoretically yield the maximum net number of molecules of ATP by substrate level phosphorylation in glycolysis: a molecule of sucrose, two molecules of glucose or two molecules of fructose?
The correct folding of proteins is necessary to maintain healthy cells and tissues. Unfolded proteins are responsible for such neurodegenerative disorders as Alzheimer's, Huntington's, and Creutzfeld-Jacob disease.
in many developing countries diseases from inadequate water supply and water contamination are a major cause of
what is the most prevalent nematode in humans in the U.S.A.? A) NAECATOR americanus B) Dictyocaulus filaria C) Uncinaria lucasi D) Enterobius vermicularis E) Loa loa
How does inefficient transfer of energy among trophic levels result in the typically high endangerment status of many top predators.
In weightless condition, body tends to. The energy for supporting a high intensity exercise derivesmainly from breaking down of
Explain the four categories of amino acid side chains. Determine what types of interactions are the members of each of these categories likely to make?
There are two autosomal recessive traits (one and two). A father has genotype Oott, and the mother has genotype OoTt. (a) Assuming that both traits are due to linked autosomal genes that are 10cM apart, calculate the probability that the indicated ..
Why is it important to take a baseline measurement of oxygen generation rate in the dark before taking readings of the organisms at different light levels?
It is frequently when the environment changes in some way that is unfavourable to an existing population that the organisms begin to reproduce sexually. Explain the importance of this switch from asexual to sexual reproduction.
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