Reference no: EM133329038
Chemical: Acrylamide:
Question 1. You are an employee of the environmental protection agency. You are charged with holding a townhall meeting following the spill. Please summarize the potential hazards of the chemical to the local population in approximately two paragraphs. Information to be included should be the chemicals normal use, the potential exposures routes following the spill, and potential health effects from exposure to the chemical. Its important to use lay terms to communicate this information to the public. In the final sentance or two you must convince the folks at this meeting that though this chemical is a known hazard that work must still be done to determine whether they are at risk. You should use primary sources to support the hazard assessment.
Question 2. If you did not already have a reference dose (RfD) or a maximum contaminant level (MCL) for the chemical, you would need to design an experiment to determine such a value. You have the following information available: The contaminated lake is the only drinking water source for the local population. The population that drinks from the contaminated lake is primarily made up of retired adults, though they occasionally have visits from their grandchildren. You only have one year to complete the study. Please provide a toxicity test design to determine a reference dose for the chemical. What uncertainty factors would you build into your RfD or MCL?
Question 3. After partitioning in the lake, the final concentration of the chemical in the drinking water is 0.0011 mg/L. The average member of the population surrounding the lake drinks 2 liters of water per day for 365 days per year for 20 years and weighs 75 kg. The averaging time for the population is 365 days per year for 20 years. What is the calculated daily intake rate for this population? Please show work?
Question 4. The following RfD values were determined from the experiments which already include adjustment for uncertainty:
Dieldrin: 5 x 10-5 mg/kg/day
Acrylamide: 3 x 10-4 mg/kg/day
Benzene: 1.7 x 10-7 mg/kg/day
While conducting a deterministic risk assessment you must calculate a hazard quotient. What is the hazard quotient for the chemical at this site? Please show your work.
Question 5. Based on the calculated hazard quotient would you conclude that there is risk to the population surrounding this lake? Please explain why (what does the hazard quotient indicate).