Study of nonmetastatic osteosarcoma

Reference no: EM131038556

Table 5.14 is from a study of nonmetastatic osteosarcoma described in the LogXact 7 manual (Cytel Software, 2005, p. 171). The response is whether the subject achieved a three-year disease-free interval.

a. Show that each predictor has a significant effect when it is used individually without the other predictors.
b. Try to fit a main-effects logistic regression model containing all three predictors. Explain why the ML estimate for the effect of lymphocytic infiltration is infinite.
c. Using conditional logistic regression, conduct an exact test of the hypothesis of no effect of lymphocytic infiltration, controlling for the other variables. Interpret.
d. Using conditional logistic regression, find a 95% confidence interval for the effect in (c). Interpret.

Reference no: EM131038556

Questions Cloud

Test the hypothesis of equal probabilities : About how large a sample is needed to test the hypothesis of equal probabilities so thatP(type II error)=0.05 whenπ1 = 0.40 andπ2 = 0.60, if the hypothesis is rejected when the P-value is less than 0.01?

Differentiate between a review and a theoretical articl : Describe how to include quotations in an APA-style paper. What "rules" are prescribed (see chapter 6)? Describe how you cite sources of quoted material. What is the quote length over which APA requires you to get the author's permission to include..

Prediction equations when each predictor : Table 5.15 describes results from a study in which subjects received a drug and the outcome measures whether the subject became incontinent (y = 1, yes; y = 0, no). The three explanatory variables are lower urinary tract variables that represent d..

Write a summary paper about the age of individualism : Write a summary paper about The Age of Individualism. IN the future, it seems, there will be only one "ism" - Individualism - and its rule will never end.

Study of nonmetastatic osteosarcoma : Table 5.14 is from a study of nonmetastatic osteosarcoma described in the LogXact 7 manual (Cytel Software, 2005, p. 171). The response is whether the subject achieved a three-year disease-free interval.

Prepare sales pitch speech that includes motivated sequence : Prepare a short 1-2 minute sales pitch speech that includes all 5 steps of Monroe's motivated sequence: Attention, Need, Solution, Visualization, Call to Action.

Pros and cons of evidence-based medicine : Discuss the pros and cons of evidence-based medicine. What can be done to increase the adoption of the beneficial aspects of evidence-based medicine in the U.S.?

Make large-sample analyses questionnable : In the previous exercise, the small cell counts make large-sample analyses questionnable. Conduct small-sample inference, and interpret.

The effectiveness of immediately injected : Table 5.13 refers to the effectiveness of immediately injected or -hourdelayed penicillin in protecting rabbits against lethal injection with β-hemolytic streptococci.

User Account

All Pages