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Study guide on mucosal immunity

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Reference no: EM132695834

Study Guide on Mucosal Immunity

What is the function of regulatory T cells?

How does expression levels of PRRs like TLR-2, TLR-4 and TLR-9 influence whether a tolerogenic or inflammatory response is generated by immune cells in Peyer's patches?

Why it is likely that only pathogenic microbes would penetrate into the crypts areas of the intestinal epithelium?

How do metabolic by-products of the normal flora influence the behavior of dendritic cells in Peyer's patches, leading to tolerogenic immune responses to intestinal normal flora?

What role do B1 cells play in mucosal immunity?

What features of IgA make it particularly suitable for secretion into mucosal tissues to provide immune protection and support a homeostatic relationship with the normal flora?

What happens in GALT when PAMPS bind to TLR-9 receptors on the basal and lateral surfaces of epithelial cells in the crypt regions?

Why are TH1, TH2, and TH17 cells formed when pathogenic microbes get into the crypt regions of the intestine?

What are differences in function of inductive compared to effector sites in mucosal-associated lymphoid tissues?

What is meant by common mucosal immunity?

Why might a vaccine delivered into NALT provide protection against a virus infecting the reproductive tract?

Reference no: EM132695834

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