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Competitive inhibition is a strategy for controlling theactivity of an enzyme. In this mechanism and inhibitor molecule, l,binds to the active site of an enzyme, E, blocking it fromprocessing its substrate
a) Derive the Michaelis Menten rule with the idea that E cannow be in any of the 3 statesPE + PES + PEl = 1 .
b) Solve for the reaction velocity, v in terms of theuninhibited enzyme (KM & Vmax),Keq,l and the total concentrations of the inhibitor,cl and substrate cs.
c) Ethanol and methanol are 2 similar, small molecules.Methanol is quite toxic: The liver enzyme alcohol dehydrogenaseconverts it to formaldehyde, which can cause blindness (hence thedanger of drinking homemade distilled alcohol). The kidneys willeventually remove methanol from the blood, but not fast enough toavert this damage. Why do you suppose the treatment for methanolpoisoning involves gradual intravenous injection of ethanol?
A person has a tidal volume (TV) of 450 mL and his anatomical dead space (ADS) is 150 mL. His respiratory rate is 10 breaths per minute. What is his alveolar ventilation rate? please show calculation and correct units.
What are the properties of Water? Explain the role of the methanotrophs in the carbon cycle. What is the best way to isolate an anaerobic, endospore-forming bacterium from its natural environment.
A stock homozygous for three recessive autosomal genes, a, b,and c, not necessarily linked on the same chromosome, ismated to a stock homozygous for their dominant wild-typealleles.
Which of the following is most apt to increase body temperature?
How can the following solutions be prepared?
Assume you work in a cool professor's Drosophila lab and you are told to figure a genetics problem regarding fly hairness.
What events in the viral life cycle take place in the nucleus?
what are four natural occuring enzymes used in Recombinant DNA technology, and describe their natural and technological use.
With the completion of the human genome and the identification of various genes, it may be possible to determine whether an individual has a particular disease.
Describe how the structure of an antibody relates to binding antigen (include a description of HV, FR, and Fab).
Four sisters begin attending your school. One has brown hair and brown eyes. Another has brown hair and blue eyes. The third also has blue eyes, but blond hair.
You have measured the absorption of pNP created by acid phosphatase after 12.5 minutes of reaction to be 0.188. The reaction occurred in a 500. µL volume into which was added 0.200 mL of 0.400 mg/mL WAP.
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