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CH3404 Asymmetric Synthesis of Pharmaceuticals and Natural Products
Knowledge• Appreciate the range of synthetic methods available to prepare enantiomerically pure molecules.• Know the strategies and reagents required to generate and implement new stereochemical elements within target-oriented syntheses.• Identify key problems in both small-scale academic synthesis and large scale industrial synthesis of stereochemically pure compounds.• Identify different reaction technology equipment and summarise the key criteria to consider before using it.
Understanding• Understand the principles and strategies of stereoselective alkene functionalization.• Understand main principles in the use of enabling technologies and related industrial issues together with application to target molecules.• Recognize where organocatalysis can be applied in synthesis and which strategies in this area are available.• Explain when alternative tools and techniques may offer significant benefit to a desired reaction outcome.
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