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Heart disease patients often experience spasms of the coronary arteries. Because biological amines such as serotonin may play a role in these spasms, a research team measured serotonin levels post-mortem from patients who died of heart disease and from a control group that died of other causes. The data are summarized in the following table:
Serotonin levelHeart disease controlsMean 3.840 5.310Standard error 850 640Number 8 12
1 Do patients dying of heart disease have serotonin levels significantly different from patients dying of other causes? Justify your answer statistically at the 5% significance level. (Which test did you use? Are you justified in assuming that the variances of the two populations are equal?)
2 Given the data, if you were told the serotonin level in the coronary arteries of a cadaver, could you make a fairly confident prediction of whether heart disease was involved? Explain.
What are the 2 ways in which researchers assess the reliability of their measures? Be sure you understand the difference among these 2 approaches to reliability.
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We suggest that you use the graphical approach to CVP analysis to solve the following problem, but you may use any other method to find the answer.
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