Reference no: EM133405987
Questions
1. The therapeutic index of a particular drug is calculated by determining the ratio of the dose that produces __________ in 50 percent of individuals divided by _____________.
A. desired effects; the dose that produces no effect in 50 percent of individuals
B. desired effects; the dose that produces toxic effects in 50 percent of individuals
C. no effect; the size of the intended population for drug administration
D. toxic effects; the typical dose that is recommended by the drug manufacturer
E. toxic effects; the dose that produces toxic effects using a similar established drug
2. Which statement regarding cerebrospinal fluid (CSF) is correct?
A. CSF is produced by the arachnoid granulations.
B. The total brain volume of CSF is about 1250 ml.
C. CSF carries nutrients to neurons.
D. More than 12 hours are required to replace half of the CSF volume in a human brain.
E. CSF helps to cushion and protect the brain.
3. Which statement is true regarding drug sensitization?
A. Drug sensitization involves a progressive decrease in behavioral actions of a drug over time.
B. Drug sensitization is more common than is drug tolerance.
C. Drug sensitization may develop for some effects of a drug, whereas drug tolerance may develop for other effects.
D. Drug sensitization involves a decrease in the number of drug receptors at the site of action.
E. Most drugs produce some form of sensitization.