Reference no: EM13205814
The compound malonate is an analog of succinate and is a strong inhibitor of succinate dehydrogenase. The active site of the enzyme will bind to either molecule, however malonate will not undergo any reaction and gets stuck on the enzyme.
Having this in mind answer the following questions with explanation
A) How many NADH's will be produced from the introduction of a single pyruvate molecule to the mitochondrion that is poisoned with malonate (assume that there are adequate amounts of all needed substances)?
B) How many FADH2's will be produced from the introduction of a single pyruvate molecule to the mitochondrion that is poisoned with malonate (assume that there are adequate amounts of all needed substances)?
C) How many ATP's will be produced from the introduction of a single pyruvate molecule to the mitochondrion that is poisoned with malonate (assume that there are adequate amounts of all needed substances)?
2. Assume that you have a normal mitochondrion in a normal cell (there are no inhibitors present). The amino acid glutamate can be converted into alpha ketoglutarate which then can enter the Citric Acid Cycle.
A) If glutamate is the only metabolite present (no acetyl CoA is present) , what intermediate of the cycle will accumulate as glutamate enters the Krebs Cycle or where will it stop? Explain.
B) How many NADH's will be produced by the metabolism of a single molecule of glutamate in the Citric Acid Cycle?
C) How many FADH2's will be produced by the metabolism of a single molecule of glutamate in the Citric Acid Cycle?
D) How many ATP's will be produced by the metabolism of a single molecule of glutamate in the Citric Acid Cycle?
E) How many carbon dioxide molecules will be produced by the metabolism of a single molecule of glutamate in the Citric Acid Cycle?
F) How many oxygen molecules are normally used during the Citric Acid Cycle?
|
Does society receive more welfare to have natural monopolies
: Identify the incentives to produce and price the product for a traditional monopoly and natural monopoly. Is it best for society, i.e., does society receive more welfare, to have natural monopolies provided by a private firm or by the government
|
|
Explain small table along with one sample calculation
: Calculate the five points indicated in the experiment introduction and show these values in a small table along with one sample calculation.
|
|
What are the required rates of return
: What are the betas of stocks X and Y, what are the required rates of return on stocks X and Y
|
|
What are the profit maximizing levels of price and output
: Customers to Live Theaters, Inc. can be divided into two groups: seniors and everyone else. The inverse demand curves for each of the two groups are given below. The marginal cost (which equals the average variable cost) of serving an additional p..
|
|
State the compound malonate is an analog of succinate
: The compound malonate is an analog of succinate and is a strong inhibitor of succinate dehydrogenase. The active site of the enzyme will bind to either molecule, however malonate will not undergo any reaction and gets stuck on the enzyme.
|
|
What is the theoretical ex-split price
: The current share price is $8.13. What is the theoretical ex-split price? Are the shareholders better off after the split, why or why not?
|
|
Explain what temperature might it become spontaneous
: From the values of delta H and delta S, predict which of the following reactions would be spontaneous at 25*C:
|
|
What is opportunity cost of attending college for one year
: Suppose that your tuition to attend college is $24,000 per year and you spend $8,000 per year on room and board. If you were working full time, you could earn $30,000 per year. What is your opportunity cost of attending college for one year
|
|
Compute the ph at the six points of titration
: Calculate the pH at the 6 points of titration (fraction titrated = 0, 0.25, 0.50, 0.75, 1.0, 1.25). Hint: Since these concentrations are not the same, first calculate the volume of NaOH required to reach the equivalent point.
|