State compound treated with silver hydroxide and heated

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Reference no: EM13174691

In the Hofmann Degradation of amines an amine is exhaustively methylated with Methyl Iodide and the resultant compound treated with Silver Hydroxide and heated. An alkene is formed which is not the Saytzeff product.

a. Illustrate this series of reactions using sec-butyl amine (2-aminobutane) as the original amine.

b. Give the mechanism for the E2 formation of the alkene in the Hoffmann Degredation..

c. Explain why the less substituted alkene forms. Use Newman projections in your discussion.

Reference no: EM13174691

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