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The resting potential of a cell is -71.5 mV assuming conductance ratios of gK:gNa:gCl = 1: 0.02: 0.03 and equilibrium potentials of EK=-70mV, ENa=+50mV, ECl=-55mV. a. Assume that the conductance ratios change to gK:gNa:gCl = 1:40:0, as might happen at the peak of the action potential. What is the membrane voltage under this condition? b. Calculate the peak of a Calcium-based spike. Assume gK:gNa:gCl: gCa = 1:0:0:40. Is this more or less than the peak of the Sodium-based spike? Given that both conductances are the same, explain the discrepancy (1 sentence). Use ECa=+125mV. Goldman equation may be of help:
c. Draw the balance model for i) the peak of the sodium based action potential and ii) the peak of the calcium based action potential.
Why did the successful cloning of Dolly the sheep support the idea that the differentiation of different cell types observed in development is orchestrated by gene regulation.
How many genes are involved in the growth behavior phenotype, and what must the genotypes in the cross be? Assume recessive loss-of function mutations are involved.
What is the advantage of having a cerebrum that is highly convulated? What term is used to indicate its grooves? Its outward folds? What groove divides the cerebrum into two hemispheres? What divides the parietal from the frontal lobe? The parietal f..
To determine the total protein content in a particular fraction, what must you multiply by what? Hint: there are 3 quantities!
A harder one which requires a little more algebra. You have 90.00 mL of dH20. How much glycerine would you have to add in order to make exactly a 1 percent (v/v) dilution?
Phosphorous is needed to synthesize the deoxyribonucleoside thriphosphates used in DNA replication. A geneticist grows some E. coli in a medium containing nonradioactive phosphorous for many generations.
community health scorecards are a great way of tracking progress in improving the health of a community. what
Draw a conscious action pathway and describe the role of this pathway, what are the effects of this pathway on the health of human? provide an example of when a conscious action is used in driving?
In mapping a large plasmid you notice that the restriction enzyme HaeII yields three bands, Pst I yields five bands and HaeII+PstI double digestion gives rise to six bands.
Describe the etiology, pathophysiology, and manifestations of pneumonia, tuberculosis, pulmonary hypertension, and cor pulmonale.
Explore the concept of an ocean front. How do they form? What is their role biologically?
Gene frequencies for the ABO alleles vary geographically. For example the I^A allele makes up nearly 50 percent of the genes for blood type among Australian Aborigines, about 25 percent in Central Asian populations,
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