Spontaneous direction of a metabolic reaction

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The spontaneous direction of a metabolic reaction is dictated by the ratio of substrate and products under equilibrium conditions (K) and under cellular conditions (Q). Compare the two reactions A→B and C→D. 

For A→B, ΔG° = -13 kJ/mol.

For C→D, ΔG° = 3.5 kJ/mol.

The cellular concentrations are as follows: [A] = 0.050 mM, [B] = 4.0 mM, [C] = 0.060 mM, and [D] = 0.010 mM. 

Which statement below correctly describes the relationship between Q and K for both reactions? Are these reactions spontaneous as written under cellular conditions?

Choose one:

A. Q > K for both reactions. Both are nonspontaneous at those concentrations of substrate and product.

B. Q > K for A→B; Q < K for C→D. A→B will be nonspontaneous at those substrate and product concentrations; C→D will be spontaneous.

C. Q < K for A→B; Q > K for C→D. A→B will be spontaneous at those substrate and product concentrations; C→D will be nonspontaneous.

D. Q < K for both reactions. Both are spontaneous at those concentrations of substrate and product.

Reference no: EM132439460

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