Smoking history presents with shortness of breath

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A middle aged adult with a 32 pack year smoking history presents with shortness of breath, with episodes of wheezing, which has become worse in the past few months. A chest x ray reveals hyperinflation of the lungs and flattened diaphrams. If a biopsy were taken of the patient's lungs, what changes would most likely be observed under the microscope? Extensive fibrosis throughout the lung parenchyma Hyperplasia of goblet cells within the bronchial walls Thickening of the alvelar-capillary membranes A decreased number of septae between alveolar spaces.

Reference no: EM133650515

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