Side effects of taking non-steroidal anti-inflammatories

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One of the side effects of taking non-steroidal anti-inflammatories like aspirin and ibuprofen is a degradation of the integrity of the stomach lining. This is because the cyclooxygenase-1 (COX-1) enzyme responsible for part of the signaling cascade that leads to replenishment of the stomach lining is inhibited by these drugs. How does it differ from the COX-2 enzyme responsible for inflammation?

Reference no: EM13162647

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