Sickle cell trait and sickle cell disease

Assignment Help Biology
Reference no: EM132955001

Use the following information to answer the next two questions.

Sickle cell anemia is a disease that is caused by a mutation in the gene that produces hemoglobin. Hemoglobin carries oxygen in red blood cells. The HbA allele produces normal hemoglobin and the HbS allele produces hemoglobin that sticks together and causes red blood cells to sickle. Heterozygous indivuals (HbAHbS) produce both normal and "sickle" hemoglobin so the HbA and HbS alleles are codominant. Heterozygotes do not develop sickle cell anemia and are described as having the sickle cell trait. Individuals that are homozygous for the sickle allele (HbSHbS) only produce "sickle" hemoglobin and develop sickle cell disease.

Note: Individuals that have sickle cell trait and sickle cell disease have protection against malaria so the HbS allele is higher in areas where malaria is common.

A man who is homozygous for the normal allele married a woman with the sickle cell trait. What is the expected probability of this couple having a boy with the sickle cell trait?

Record your answer as a value between 0 and 1 rounded to two decimal places.

Reference no: EM132955001

Questions Cloud

Discuss sympatric speciation : Then use the example of the Lake Apoyo cichlids on pages 195-196 of The Tangled Bank to discuss sympatric speciation.
Compare the modes of transmission of infectious disease : Identify and compare the modes of transmission of infectious disease providing at least one example of a pathogen that can be transmitted by each mode identifie
Explain why scientific experiments need many replicates : Explain why scientific experiments need many replicates. Use one or more examples.
Number of dominant alleles genotype phenotype : Below is a simplified chart for polygenic trait of eye colour. The amount of melanin in the iris is what determines the colour of the eye. People with brown eye
Sickle cell trait and sickle cell disease : Sickle cell anemia is a disease that is caused by a mutation in the gene that produces hemoglobin. Hemoglobin carries oxygen in red blood cells. The HbA allele
Write the expected genotypes and expected phenotypic ratio : In Cacti one gene determines whether the cactus will have spines (S dominant) or no spines (s recessive). A second gene determines whether the spines are pointe
Human overpopulation disrupts biodiversity : Issue: Human overpopulation disrupts biodiversity and the environment
Should eating meat be outlawed : Should eating meat be outlawed? Discuss both sides of this argument in relation to the macromolecules in grade 12 biology and other areas of grade 12 biology. C
Create a diagram of a tree : a) Develop a FLOW CHART to illustrate the life cycle of the tree. Make sure to include where the processes of photosynthesis and transpiration occurs.

Reviews

Write a Review

Biology Questions & Answers

  Immune response to infectious disease

It is a very curcial concept to understand how the immune response is mounted against viruses, bacteria, protozoans and helminthes. For an effective immune response, both innate and adaptive immunity should work together.

  A review on advanced glycated end products (ages)

This Project report elaborates a critical review of important elements attached to Advanced Glycated End Products (AGEs). It is very crucial to understand the process called Millard reaction.

  Plastic as a soil stabilizer

Soil stabilization is the permanent physical and chemical alteration of soils to enhance their physical properties. Stabilization can increase the shear strength of a soil and control the shrink-swell properties.

  Principles of microbiology

This assignment has three parts which contains questions related to Microbiology. It contains basic principles of microscopy, staining techniques in microbiology and microbial growth in the food industry.

  List the biologic functions

Lipid metabolites are often seen as key elements in cellular signaling. Is this unique? Please provide several examples of the function of lipids as key elements in signal arrays and list the biologic functions these signals affect?

  Biologic function relationships

Please describe how one might search for chemical structure, biologic function relationships, involving small molecular weight lipophylic compounds. Provide one example.

  Case study on patient in the haematology laboratory

Write a case study which detailing a scenario of a patient being investigated in the Haematology laboratory.

  Use of pcr and genetic approaches in biotechnology

The use of PCR and genetic approaches in biotechnology

  Describe the role of this enzyme in honey

Glucose oxidase is an enzyme that can be used for measurements of glucose levels by combining this reaction with an oxygen probe.

  Genetic problems

What phenotypic ratio would you get if you crossed a white mouse and a heterozygous brown mouse?

  Prepare an essay on nosocomial infection

Prepare an essay on nosocomial infection.

  Monitoring and recording the blood pressure

To increase the awareness of monitoring and recording the blood pressure of patients and practice measuring blood pressure in a safe environment.

Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd