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Remdesivir
a. Remdesivir absorbs strongly in the UV (Amax - 260 nm). Show on the structure above the chromophore of remdesivir
b. Remdesivir is not significantly fluorescent. Which of the following ranges characterizes its fluorescence quantum yield?
0 to 0.2 0.2 to 0.4 0.4 to 0.6 0.6 to 0.8 0.8 to 10
c. As an adenosine analog, the major pathway for the excited state relaxation of remdesivir is external conversion. Please name two approaches that could be expected to improve the fluorescence of remdesivir.
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