Shortness of breath and fatigue during physical activities

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Mr. Johnson, a 55-year-old male, presents to the cardiology clinic with complaints of shortness of breath and fatigue during physical activities. He has a history of hypertension and was recently diagnosed with heart failure with reduced ejection fraction (HFrEF). Considering potential therapeutic strategies, which intervention could improve cardiac function in HFrEF by modulating (i.e., reducing) phospholamban activity?

Reducing calcium intake in the diet. Preventing phospholamban from being activated Increasing phospholamban activation

Reference no: EM133704878

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