Role of a nutrition professional in nutritional genomics

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The human genome is estimated to encode over 30,000 genes, and to be responsible for generating more than 100,000 functionally distinct proteins. Understanding the interrelationships among genes, gene products, and dietary habits is fundamental to identifying those who will benefit most from or be placed at risk by intervention strategies. Unraveling the multitude of nutrigenomic, proteomic, and metabolomic patterns that arise from the ingestion of foods or their bioactive food components will not be simple but is likely to provide insights into a tailored approach to diet and health. The use of new and innovative technologies, such as microarrays, RNA interference, and nanotechnologies, will provide needed insights into molecular targets for specific bioactive food components and how they harmonize to influence individual phenotypes.

Undeniably, to understand the interaction of food components and gene products, there is a need for additional research in the "omics" of nutrition. It is incumbent upon dietetics professionals to recognize that an individual's response to dietary intervention will depend on his or her genetic background and that this information may be used to promote human health and disease prevention. The objectives of this review are to acquaint nutritional professionals with terms relating to "omics," to convey the state of the science to date, to envision the possibilities for future research and technology, and to recognize the implications for clinical practice.

Nutrigenomics is the scientific study of the way specific genes and bioactive food components interact. It provides a basis for understanding how the health consequences of eating behaviors may vary across individuals. The concept of nutrigenomics builds on the premises that:

  • diet and dietary components can alter the risk of disease development by modulating multiple processes involved with onset, incidence, progression, and/or severity;
  • food components can act on the human genome, either directly or indirectly, to alter the expression of genes and gene products;
  • diet could potentially compensate for or accentuate effects of genetic polymorphisms; and
  • diet could potentially compensate for or accentuate effects of genetic polymorphisms; and

The study of nutrigenomics and/or associated changes in proteomics and metabolomics could ultimately identify molecular targets for nutritional preemption. This information is key to a personalized approach to nutrition, which will ultimately distinguish responders from nonresponders. The objectives of this review are to acquaint nutrition professionals with terms relating to "omics," to convey the state of the science to date, to envision the possibilities for future research and technology, and to recognize the implications for clinical practice.

Based on the above text assist with the questions below

Using the information presented in the text and articles, what is the role of a nutrition professional in nutritional genomics? Should we modify or change recommendations we make to prevent diabetes, obesity, and cancer based on nutritional genomics and ethics? Why or why not? Are gene-environment interactions relevant to public health nutrition?

Use Scripture to support your assertations and represent your Biblical worldview of nutritional genomics.

Reference no: EM133706868

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