Replicating the ends of linear chromosomes

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The process of DNA replication creates a particular problem for replicating the ends of linear chromosomes.

a) Describe why the DNA replication machinery has difficulty replicating DNA ends.

b) Telomerase has been identified as an enzyme that can reverse the outcome of end replication. Describe the near-universal mammalian chromosome telomere sequence and how telomerase solves the problem of end replication.

Reference no: EM131887882

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