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a. Analyze the DNA of the Phenylalanine hydroxylase (PAH) gene in a patient with phenylketonuria revealed a mutation in the protein coding region whose predicted effect would be to replace the amino acid aspartic acid, with histidine. Nevertheless, no mutant protein could be found in the patient’s cells. Briefly explain how this could happen.
b. How is it possible for a gene with a mutation in the coding region to encode a polypeptide with the same amino acid sequence as the non?mutant gene?
A mammal uses only one to two percent of its energy in ventilation as a fish must spend about 15 percent of its energy to move water over its gills. Explain this huge difference in their efforts to collect oxygen.
explain Why is it advantageous for citrate the product of reaction 1 of the TCA, to inhibit phosphofructokinase, which catalyses the third reaction in glycolysis.
Assume you have a population of 3,320 AA; 640 Aa; and 12 aa genotype. Calculate the relative fitness w, and the selection coefficient for each 3 genotypes
Application of an insecticide to control mosquito populations in malaria infested areas quickly resulted in a dominant mutation, R, resulting in insecticide resistance.
What is the significance of adenine, thymine, guanine, and cytosine in the structure of a DNA molecule.define how these four nucleotides bond.
Dialysis patients, who will have blood withdrawn, dialyzed, then replaced, are always weighed while they enter the facility and then weighed carefully before they leave. What is the most probable explanation for this requirement.
What is the possibility that the son would have both the Xg antigen and ichthyosis. Why is the man a major candidate for a heart attack.
Compare and contrast gene expression in prokaryotes vs. eukaryotes from the standpoint of promoter sequences
Assume you make buffer solution by adding four gram sodium bicarbonate to 270 milliliters of water then titrate this solution to 30 ml of 0.1 molar HCl and find the equilibrium equation for this base/acid pair.
Is this an instance of a positive or negative feedback mechanisms? What is the initial stimulus? What is the result.
A system is given by two compartments separated through a thin membrane, and solute moves from one compartment to the other through diffusion. The volume of compartment 1 is 0.03 cm^(3) and compartment 2 is 0.01 cm^(3).
Discuss why is the ovulate cone of a pine designed to be so much more durable than the staminate cone? Find the advantage of having seeds rather than spores?
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