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Hydrocortisone (Solu-Cortef) and Dexamethasone (Decadron) are used as replacement therapy in a deficiency state, specifically. Nursing considerations include monitoring BP and HR before and after administration. Never abruptly stop the medication as well as educating on taking medication as directed and to not suddenly stop medication as it could lead to an adrenal crisis. The nurse should always taper the dose. Monitor for side effects, especially those resulting in Cushing disease (weight gain, hyperglycemia, hypertension, edema, easy bruising, muscle weakness, red round face, depression, mood swings). Assess and monitor prior and during therapy for signs of adrenal insufficiency (hypotension, weight loss, weakness, nausea, vomiting, anorexia, lethargy, confusion, restlessness, poor feeding, fatigue, low muscle tone, joint pain, hypoglycemia). Monitor I&Os and daily weights.
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