Reduction of fitness of the heterozygote

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1. Albinism is due to a recessive, autosomal mutation. The frequency of albino squirrels is 4 x 10^-6, while heterozygous squirrels, which are tan colored(and are lighter than wild-type squirrels), occur at frequency 0.004. Assume the population in at mutation-selection balance.

a. What is the frequency of the albino allele? Show work.

b. If the mutation rate to new albino alleles is 10^-6, what is the reduction of fitness of the heterozygote?

2. Assume that in a one locus, two-allele system, the frequency of the A allele is p and the population is in Hardy-Weinberg equilibrium. Now, assume we catch a single random female, randomly collect two eggs from her, and determine the genotype of each of these eggs. What is the probability that we will get two eggs carrying the A allele? Express the answer in terms of p.

Reference no: EM131957420

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