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Reasons for storage of transmitters in vesicles

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What are three reasons for storage of transmitters in vesicles as opposed to letting them be free in the terminal? (a) neurotransmitter can be concentrated (typically vesicles contain 5000 - 10,00C molecules) - massively increases chances of some transmitter getting across synaptic cleft to post-synaptic receptors,- (b) neurotransmitter can be preserved from degradation by cellular enzymes, and (c) release of neurotransmitter can be controlled so it is used only for the speci?c purpose of transferring signal from Dre-synaptic neuron to the post-synaptic structure.

Reference no: EM132933409

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