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Peripheral arterial disease involves blockages in one or more arteries in the leg. Patients with peripheral arterial disease typically experience pain while walking, and there are potentially serious complications associated with the disease. A group of investigators are interested in comparing the effect of a 12-week structured exercise therapy program versus stenting (a revascularization procedure for the leg) on the outcome "distance able to walk without pain" for patients with PAD.
1. What are the strengths and potential limitations of using a randomized clinical trial study design to test this hypothesis? Use your own words and answer the question in terms of the population, interventions, and outcome under consideration.
2. Briefly describe how the patients who are eligible but "refuse enrollment" could affect the internal validity or the generalizability of the study? Describe how patients who "discontinue intervention" could affect the internal validity or the generalizability of the study?
You have been given a 1.0 kbp human genome fragment that does not contain any repeated sequences. Your plan is to use it as a probe for a Southern Blot
Describe the role of transporter proteins with regard to nutrient movement
What you would need to demonstrate in order to infer that ecological speciation is the mechanism that generates this reproductive barrier.
In the protein structure, label four different elements of secondary structure with an arrow.
Scientific advances are pointing researchers to new ideas about how to reduce the side effects of epilepsy medications and improve therapy options for those resistant to current medications.
Week thread discussion: mechanisms of antibiotic resistance (3-4pgs) What are five general mechanisms of antibiotic resistance and explain them. Who is David Livermore and what is his research about regarding it. solution? knowledge of antibiotic res..
Suppose that Mendel looked simultaneously at four traits of his pea plants. If he crossed a homozygous dominant plant with a homozygous recessive plant.
What does the term "action" mean when speaking of skeletal muscle contraction? Choose muscle/provide explanation of its action.
If sigma(70) and RpoS recognize different promoter sequences, and some genes have both a sigma(70) promoter and an RpoS promoter, then explain how either sigma factor could activate transcription of those genes.
Describe the homeostatic compensations that occur throughout the body?
1. Discuss the evolution of the knowledge of microorganisms as the cause of diseases in humans?
Knowing that acid rain has a pH of 2 - 3 would you conclude that crop species with a narrow soil pH range are in trouble? Explain why, or why not, using scientific reasoning. Is acid rain a problem for plant species and crops?
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