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1- One recent approach to vaccine development has been production of peptide vaccines. In these vaccines, antigenic peptides are injected instead of whole bacteria or viruses. Peptide vaccines have not been particularly useful against viral pathogens because viral infections require a CD8+ T cell mediated immune response. Why is a peptide vaccine unable to create such a response?
2- In type I insulin dependent diabetes, CD8+ T cells specifically target and destroy insulin producing b cells in the islets of Langerhans in the pancreas. How is MHC class I involved? "diabetes is not caused by a virus or intracellular bacterial infection"
3- The parasite, Toxoplasma gondii, invades cells and replicates inside its own vesicle which does not fuse with any cellular vesicles. Why is this parasite unable to be presented with class II MHC?
What is the connection between an increase in light intensity and photosynthetic rate in leaves from a corn plant? How does this relationship compare with what you observed for tomato plants.
Two true breeding pea plants were crossed. One parent is round, terminal, violet, constricted, while other expresses the respective contrasting phenotypes of wrinkled, axial, full.
Explain the nonspecific antimicrobial effects of mucus, lysozyme, and low pH. For each of these substances, list where they are found in the body and how they function in fighting pathogens.
Show the lines of current flow to unexcited parts of the cable. Elucidate how these local currents cause the action potential to propagate. A common mistake is to confuse the currents that flow throughout the action potential the voltage-clamp curren..
Explain why people addicted to methamphetamines often sleep very little, suffer extreme mood swings, and become very thin.
A small, impermeable membrane is placed between the anchor cell and the other vulva precursor cells in a larva of C. elegans. What would you expect the result to be.
Assume you are testing a hypothesis that population density of a particular plant species influences the rate at which a pathogenic fungus infects the plant.
Explain how black and white pattern on the male siamese cat arises. If the oceans warm a few degrees, what impacts can you see on the landmasses, biologic community, and human populations? Are these positive or negative changes? Why with reason.
Achondroplasia is caused by an autosomal dominant mutation within the fibroblast growth factor receptor-3 gene on the short arm of chromosome four.
In a certain plant, fruit is either red or yellow, and fruit shape is either oval or long. Red and oval are the dominant traits. Two plants, both heterozygous for these traits.
Assume your supervisor has found a new test kit that she wants to start using. She has asked you to validate the kit. Please explain some tests that might be needed?
One of the major categories of receptors in the plasma membrane reacts by forming dimmers, adding phosphate groups, and then activating relay proteins. Which kind does this.
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