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Q1. Hypophosphatemia (vitamin D-resistant rickets) is inherited as the sex-linked dominant trait. The relevant gene is found on an X chromosome. What is an expected outcome of a cross between a homozygous recessive woman and a man with hypophosphatemia?
Q2. A chimeric gene containing a cloned cDNA of the coat protein (CP) gene of tobacco mosaic virus (TMV) was introduced into tobacco cells on a Ti plasmid of Agrobacterium tumefaciens from which tumour inducing genes had been removed. Plants regenerated from transformed cells expressed TMV mRNA and CP as a nuclear trait. Seedlings from self-fertilized transgenic plants were inoculated with TMV and observed for expansion of disease symptoms. The seedlings that expressed the CP gene were delayed in symptom development and 10 to 60 percent of transgenic plants failed to develop symptoms for the duration of the experiments. Increasing the concentration of TMV in the inoculum shortened the delay in appearance of symptoms. The results of these experiments point to that plants can be genetically transformed for resistance to virus disease development.
A 2-amino-purine can be incorporated into DNA in place of adenine. It can pair equally well with thymine or cytosine. What type of mutation do you expect it to cause.
Explain the cardiac cycle beginning with atrial systole. Include what happens during all of the steps, including atrial systole and diastole, and ventricular systole and diastole.
What molecule is produced in the citric acid cycle as a by-product of glucose oxidation and is subsequently released into the bloodstream and carried to the lungs, where it is removed from the body?
Does biological evolution have any bearing on moral or ethical aspects of human life? Should biological evolution inform our morality? If biology has no role in discussions of ethics and morality, what should be the basis for these discussions?
How does this contribute to the symptoms of lactose intolerance? Also, why do areas with good climate for crops generally have a high incidence of lactose intolerance?
You are analyzing the structure of a gene and find it contains a restriction site for Pst1. This site is ~1000 bp away from another restriction site for Not1.
How do you determine the allelic frequency, expected genotype frequency if the population were all genetic equilibrium, and compare the calculated expected genotypic frequencies.
Would the bat be able to tell the distance to a target if, instead of the bat's out going pulse, you returned a broadband noise containing the same frequencies?
What do prion and virus have in common and what do capsid and prion have in common?
How will you find out the transcription factor binding sites in the whole genome. You have isolated a novel transcription factor. How would you decide the genes regulated by transcription factor in the whole genome.
Metallic magnesium has a hexagonal close-packed structure and a density of 1.74 g/cm 3 . Suppose magnesium atoms to be spheres of radius, r.
Write the sequence of the peptide fragments that would beformed if β-endorphin was treated with pepsin?
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