Provide the pathophysiology of sickle cell disease

Reference no: EM133272163

Question - A 38-year-old African-American woman was admitted for arthroscopic knee surgery. Her hematocrit was 25%, blood pressure was 140/94 mm Hg, and pulse was 112 beats/minute. She had a history of joint and bone pain, jaundice, and abdominal pain.

Due to the presenting symptoms (joint and bone pain, abdominal pain, and jaundice) a diagnosis of Sickle Cell Disease was considered.

Provide the pathophysiology of sickle cell disease. Discuss the clinical manifestations and etiology associated with these manifestations.

Reference no: EM133272163

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