Protein kinase transfer the terminal phosphate from atp

Reference no: EM13869576

Protein kinase transfer the terminal phosphate from ATP to specific serines, threonines or tyrosines of specific target proteins. To test these particular phosphorylation sites we use site-directed mutagenesis to convert the to-be-phosphorylated serines, threonines or tyrosines to aspartic acids or alanines. One of these is considered a non-phosphorylatable mutation and the other is a phospho-mimetic mutation. Which type of amino acid replacements is a non-phosphorylatable or a phospho-mimetic? Explain your answer.

Reference no: EM13869576

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