Propose a dna-binding mode for the compound

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(a) Based upon its chemical structure, propose a DNA-binding mode for the compound.

(b) List the types of non-covalent interactions that can stabilise the drug- DNA adduct. Indicate which fragment(s) of DNA and 1 are involved in each case.

(c) Why is 1 such an avid DNA-binding agent?

Reference no: EM132560719

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