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CH8404 Asymmetric Synthesis of Pharmaceuticals and Natural Products
Knowledge• Appreciate the range of synthetic methods available to prepare enantiomerically pure molecules.• Know the strategies and reagents required to generate and implement new stereochemical elements within target-oriented syntheses.• Identify key problems in both small-scale academic synthesis and large scale industrial synthesis of stereochemically pure compounds.• Identify different reaction technology equipment and summarise the key criteria to consider before using it.
Understanding• Understand the principles and strategies of stereoselective alkene functionalization.• Understand main principles in the use of enabling technologies and related industrial issues together with application to target molecules.• Recognize where organocatalysis can be applied in synthesis and which strategies in this area are available.• Explain when alternative tools and techniques may offer significant benefit to a desired reaction outcome.
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What volume of 2M H2S , in L, is required to react with excess O2 to produce enough SO2 to fill a cylinder that is 51ft long and has a diameter of 7ft at a pressure of 464 torr and 30 AC?
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when cooncentrated cacl2 aq is added to na2hpo4 aq a white ppt forms that is 38.7 ca by mass. write a net ionic
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Does the purified aspirin appear to purer than crude aspirin? What is your evidence?
A phosphate buffer solution (25.00 mL sample) used for a growth medium was titrated with 0.1000 M hydrochloric acid. The components of the buffer were sodium monohydrogenphosphate and sodium dihydrogenphosphate
What mass of hydrogen chloride gas is required to produce 250ml of a hydrochloric acid solution with a pH of 1.57?
the expresssion for the freezing point depression of a solution relative to that of the pure solute is shown above.
Explain what is more soluble, a solution of free histidine or a solution of histidine tetrapeptide at pH 6 net charge +2
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