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While studying the Michaelis - Menton kinetics of enzymes in the TCA cycle, the synthetic hydrocarbon malonate was shown to act as a competitive inhibitor of one of the enzymes. At first, the identity of the inhibited enzyme was unknown but further tests revealed that this inhibited TCA enzyme was unusual because it was bound to the inner mitochondrial membrane, unlike any of the other TCA enzymes.
Predict which of the TCA enzymes was inhibited by malonate; explain how you know. List details of the reactions catalyzed by the membrane bound TCA enzyme you named in the first part. Be sure to include both the TCA reaction and any redox reactions that are catalyzed by the enzyme.
An arginine residue in the matrix side proton channel of a subunit of ATP synthase is near the aspartate residue in the c ring subunit.
For every one molecule of glucose, how much total ATP via substrate level phosphorylation is made during the TCA cycle? 2. For every one molecule of glucose.
Lysosomes are single membrane-enclosed, 0.2-0.5 m diameter spherical vesicles inside the cytosol of eukaryotic cells. Estimate the concentration of H+ inside lysosomes.
Describe how you would identify E. coli mutants that cannot utilize galactose as a carbon (energy) source. You are given a test tube containing E. coli grown under full nutrition, a spreader, filter paper, Petri plates with agar gel containing var..
How much water would it take to excrete , via the salt gland, a sodium load from ingesting 100ml of sea water if the average sodium concentration of the salt gland's secretion is 600 mmil/L? (HINT : Look up the concentration of Na+ in sea water to..
If the frequency of aa genotype is 0.16, the frequency of Aa genotype is 0.48, and the frequency of AA genotype is 0.36 what are the frequencies of the A and a alleles?
Syed is a body builder. He is concerned about his protein intake. If Syed weighs 200 pounds and consumes about 3600 Calories/day, 15% of which comes from protein, will his diet supply enough protein to meet the recommendation for strength athletes..
Suppose you are a behavioral psychologist and are asked to determine to what extent intelligence (IQ) is heritable or multifactorial. That is, how much is inherited versus how much IQ results from environmental influences? How will you proceed wit..
Plants may be 10, 20, 30, 40, 50, 60 or 70 cm high where plant high is under polygenic control. A true-breeding plant that is 10 cm is crossed to another true-breeding plant that is 50 cm.
What system is not present in earthworms, but present in humans? How do you suppose the process is accomplished?
What progeny will a roan short hair have.
Assume you are interested in studying the mysterious disease SW that causes obsession with Star Wars movies or memorbilia. You decide to clone the gene in order to further study the gene function.
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