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Problem: Arsenate is very similar to phosphate both structurally and chemically. Organic compounds of arsenate are less stable than analogous phosphate compounds.
Required:
Question 1: Predict the effect on the net reaction catalyzed by glyceraldehyde 3-phosphate dehydrogenase if phosphate were replaced by arsenate.
Question 2: What would be the consequence to an organism if arsenate (AsO4) were substituted for phosphate and explain why this compound is poisonous?
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