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A 48-year-old man was admitted to the hospital for an elective cholecystectomy, and a pre-surgical workup reveals a serum sodium level of 125 mEq/L (normal 135-145 mEq/L). He complains of some fatigue, anorexia, and very mild confusion. Vital signs are all within normal limits, as is his physical examination. Urinalysis reveals a urine osmolarity of 620 mOsm/kg. Further questioning reveals a 60-pack per year history of smoking. He denies any recent vomiting or diarrhea, has a normal albumin level, and shows no signs of heart failure. He denies taking diuretics or other medications. A chest x-ray film reveals a 3-cm, spiculated pulmonary nodule near the hilum of the right lung. What is the most likely diagnosis? Nephrotic syndrome SIADH Central DI Renal artery stenosis Deficiency of aldosterone.
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