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Possible effects on lipid levels and cardiovascular

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Reference no: EM132063884

  1. A nonfunctional MTP gene/protein causes ABL. What are the possible effects on lipid levels and cardiovascular pathology if this protein is overexpressed?
  2. Based on your understanding of the role of ABCA1 in the formation of HDL particles,how would you design a therapeutic modality to overcome a weakened interaction between ABCA1 and apoA-I that results from a mutation in ABCA1 gene?
  3. How would you modulate the reverse cholesterol transport pathway to increase cholesterol ef?ux from cells in normal individuals?

Reference no: EM132063884

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