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Plasma drug concentration

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Reference no: EM133252700

Question

Consider the need to maintain a minimum plasma drug concentration of 3 mg/L for at least 8 h after administration of the intravenous dose. What amount of bolus dose is required if the elimination rate constant, ke, is 0.15 h-1 and the apparent volume of distribution is 10 L? Please enter your answer as XX.X mg.

Reference no: EM133252700

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