Perform a McNemars test and a Chi-squared test

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Statistical Packages Homework -

Please submit BOTH your program syntax and relevant output/conclusions together in one word file.

Q1. Hodgkin's Disease

In a study of Hodgkin's disease, a cancer of the lymph modes, each of 538 patients with the disease, was classified by histological type and by their response to treatment 3 months after it had begun. (The data are described in more detail in Hancock et al., 1979.) The histological types are LP = lymphocyte predominance, NS = nodular sclerosis, MC = mixed cellularity and LD = lymphocyte depletion.

 

Response

Positive

Partial

None

Total

Histological type

LP

74

18

12

104

NS

68

16

12

96

MC

154

54

58

266

LD

18

10

44

72

Total

 

314

98

126

538

1. 'What, if any, is the relationship between histological type and response to treatment?

Q2. The data in the following table represents 53 married couples and provides the number of cases in which a tall or short man was married to a tall or short woman. Perform

1) a McNemar's test

2) a Chi-squared test

Be sure to discuss the underlying hypotheses that you would accept/reject and differences/similarities between the conclusions from the two tests.


Wife

Husband

Tall

Short

Tall

18

14

Short

12

9

Q3. The data in the following table are excerpted from an article by Duggal et al. (2010). Researchers gathered data from 5 placebo-controlled studies of Niacin and heart disease. They were looking to see if the risk of coronary heart revascularization was lower when patients were given Niacin versus placebo. Accounting for the 5 different studies in your analysis, is there an association between revascularization and Niacin?

Study Name

Revasc.

No revasc.

Percent revasc.

FATS

Niacin

Placebo

2

11

46

41

4.2

21.2

AFREGS

Niacin

Placebo

4

12

67

60

5.6

16.7

ARBITER 2

Niacin

Placebo

1

4

86

76

1.1

5.0

HATS

Niacin

Placebo

1

6

37

32

2.6

15.8

CLAS 1

Niacin

Placebo

2

1

92

93

2.1

1.1

Q4. The data in the following table are excerpted from an article (Inskip et al., 2001) from New England Journal of Medicine. Is cell phones usage associated with brain tumor?

Cell Phone Use

Control Group

Brain Tumor Group

No Use

440

471

1-5 times in life

105

94

>5 time in life

232

194

Regular use

172

139

Reference no: EM132375495

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